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DeCS
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Descriptor English:
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Complement C9
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Descriptor Spanish:
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Complemento C9
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Descriptor Portuguese:
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Complemento C9
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Synonyms English:
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C9 Complement
Complement 9
Complement Component 9
C9, Complement
Complement, C9
Component 9, Complement
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Tree Number:
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D12.776.124.486.274.850
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Definition English:
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A 63-kDa serum glycoprotein encoded by gene C9. Monomeric C9 (mC9) binds the C5b-8 complex to form C5b-9 which catalyzes the polymerization of C9 forming C5b-p9 (MEMBRANE ATTACK COMPLEX) and transmembrane channels leading to lysis of the target cell. Patients with C9 deficiency suffer from recurrent bacterial infections. |
Pharmacological Action:
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Immunologic Factors
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History Note English:
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2006 (1975)
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Allowable Qualifiers English:
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Record Number:
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22140
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Unique Identifier:
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D003186
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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